Aminergic signal transduction in invertebrates : focus on tyramine and octopamine receptors

  • Electro-chemical signal transduction is the basis of communication between n eurons and their target cells. An important group of neuroactive substances that are released by action potentials from neurons are the biogenic amines. These a re small organic molecules that bind to specific receptors located in the target cell membrane. Once activated these receptors cause changes in the intracellula r concentration of second messengers, i.e. cyclic nucleotides, phosphoinositides , or Ca2+, leading to slow but long-lasting cellular responses. Biochemical, pha rmacological, physiological, and molecular biological approaches have unequivoca lly shown that biogenic amines are important regulators of cellular function in both vertebrates and invertebrates. In this review, we will concentrate on the p roperties of two biogenic amines and their receptors that were originally identi fied in invertebrates: tyramine and octopamine. 

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Metadaten
Author details:Wolfgang BlenauORCiDGND, Arnd Baumann
URN:urn:nbn:de:kobv:517-opus-44271
Publication series (Volume number):Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe (paper 107)
Publication type:Postprint
Language:English
Publication year:2003
Publishing institution:Universität Potsdam
Release date:2010/07/01
Source:Recent research developments in neurochemistry 6 (2003), S. 225 - 240
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie
DDC classification:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
License (German):License LogoKeine öffentliche Lizenz: Unter Urheberrechtsschutz
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The article was originally published by
Research Signpost:
Recent research developments in neurochemistry. - 6 (2003), pp. 225 - 240
ISBN 81-271-0021-8
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