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URN: urn:nbn:de:kobv:517-opus-14747
URL: http://opus.kobv.de/ubp/volltexte/2007/1474/
Dicken, Volker
Simultaneous activity and attenuation reconstruction in emission tomography
Kurzfassung in Englisch
In single photon emission computed tomography (SPECT) one is interested in reconstructing the activity distribution f of some radiopharmaceutical. The data gathered suffer from attenuation due to the tissue density µ. Each imaged slice incorporates noisy sample values of the nonlinear attenuated Radon transform
(formular at this place in the original abstract)
Traditional theory for SPECT reconstruction treats µ as a known parameter. In practical applications, however, µ is not known, but either crudely estimated, determined in costly additional measurements or plainly neglected. We demonstrate that an approximation of both f and µ from SPECT data alone is feasible, leading to quantitatively more accurate SPECT images. The result is based on nonlinear Tikhonov regularization techniques for parameter estimation problems in differential equations combined with Gauss-Newton-CG minimization.
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Freie Schlagwörter (Englisch): |
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SPECT , tomogrphy , attenuated Radon transform , nonlinear invers problem , Tikhonov regularization , nonlinear optimization |
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Institut 1: |
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Institut für Mathematik |
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Institut 2: |
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Interdisziplinäres Zentrum Dynamik komplexer Systeme |
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DDC-Sachgruppe: |
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Physik |
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Dokumentart: |
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c Preprint (Vorabdruck) |
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Schriftenreihe: |
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NLD Preprints |
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Bandnummer: |
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paper 050 |
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Sprache: |
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Englisch |
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Erstellungsjahr: |
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1998 |
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Publikationsdatum: |
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13.07.2007 |